Sodium channel traffic on the cardiac microtubule highway
نویسندگان
چکیده
منابع مشابه
Sodium channel traffic on the cardiac microtubule highway.
Voltage-gated sodium channels are responsible for excitable cell action potential initiation. In cardiomyocytes, SCN5A-encoded Nav1.5 is the primary voltage-gated sodium channel a subunit, although other Nav channel a subunits may secondarily modulate specific INa properties. In addition to the pore-forming Nav1.5 a subunits, four accessory Nav b subunits (b1–b4) are expressed in the human hear...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2009
ISSN: 0008-6363
DOI: 10.1093/cvr/cvp404